Endocrine Abstracts

Bisphenol A (BPA) is an environmental estrogen that is globally used in the production of plastics. Studies on BPA as an endocrine disruptor have focused on its estrogenic activity in vitro and in adult animal models. Recently, the National Toxicology Program at the US National Institutes of Health raised concerns for the neural and behavioral effects of BPA in fetuses, infants, and children at the currently allowed human exposures. However, the difficulty in studying u...

Background: A subset of Graves’ disease (GD) patients develops refractory hyperthyroidism, posing challenges in treatment decisions. The predictive value of baseline characteristics and early therapy indicators in identifying high risk individuals is an area worth exploration.Methods: A prospective cohort study (2018-2022) involved 597 newly diagnosed adult GD patients undergoing methimazole (MMI) treatment. Baseline characteristics and 3-month ther...